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What does replicability look like across a national sample of biomedical research? Join us for a conversation with members of the Brazilian Reproducibility Initiative, a large-scale, multicenter effort to systematically assess the replicability of biomedical experiments published by Brazilian researchers. In this webinar, the team will share key findings from their recently published preprint (https://www.biorxiv.org/content/10.1101/2025.04.02.645026v2), reflect on lessons learned from coordinating a national replication project, and discuss broader implications for metascience and research reform. The session will include time for audience Q&A.